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How to choose low level laser therapie?

What is low level laser therapie?

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What islow level laser therapie-low level laser therapie is a form of alternative medicine -that uses laser light at low levels or near-infrared light. The light is applied to the surface skin of the body with the intentions of decreasing pain or inflammation, promoting healing of wounds, tissues, and nerves, or for preventing tissue damage. This is much different than the high level lasers that we know for surgical procedures to cut and destroy unhealthy tissue.The lasers used in LLLT (low level laser therapie) are typically small (often handheld) units, and unlike surgical and aesthetic lasers, do not heat the targeted tissue. Instead, LLLT (low level laser therapie) emits low levels of light that are absorbed by your mitochondria (the energy-producing organelles in many of your cells), which then can increase cellular energy production and ultimately help heal surrounding tissue. This process is comparable to plant photosynthesis, during which sunlight is absorbed by plants and converted to energy for the plants to grow.

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How LLLT (low level laser therapie) work?

For low-power visible or near-infrared light to have an effect on a biologic system, the photon must be absorbed by electronic absorption bands belonging to a photon acceptor or chromophore (first law of photobiology) . A chromophore is a molecule (or portion of a molecule) which imparts a color to a compound (e.g. chlorophyll, hemoglobin, myoglobin, cytochrome c oxidase, other cytochromes, flavin, flavoproteins or porphyrins) . The “optical window” in a tissue describes a range of wavelengths where the penetration of light into tissue is maximized by employing red and near-infrared wavelengths . The optimum wavelength has been estimated to be around 810 nm. Mitochondria are “the cellular power plants” in our cells and as such they convert food molecules and oxygen into energy (ATP) by oxidative phosphorylation. It has been proposed that cytochrome c oxidase (COX) is the primary photo-acceptor for the red-NIR wavelength range in mammalian cells . Nitric oxide (NO) produced in mitochondria can inhibit respiration by binding to COX and displace oxygen especially in injured or hypoxic cells . It is proposed that LLLT (low level laser therapie) can photo-dissociate NO from COX and reverse the mitochondrial inhibition of respiration due to excessive NO binding . The process of light mediated vasodilation was first described by RF Furchgott in 1968, and his research on the biological properties of nitric oxide eventually led to the award of a Nobel Prize in 1998 . LLLT (low level laser therapie) is able to produce a shift in the overall cell redox potential in the direction of greater oxidation by increasing reactive oxygen species (ROS) and decreasing reactive nitrogen species (RNS). The long-term effects of LLLT (low level laser therapie) are thought to be due to the activation of various transcription factors by the immediate chemical signaling molecules produce from mitochondrial stimulation by LLLT (low level laser therapie). The most important of these signaling molecules are thought to be ATP, cyclic-AMP, NO and ROS .

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LLLT (low level laser therapie) at low doses has been shown to enhance cell proliferation of fibroblasts , keratinocytes, endothelial cells and lymphocytes . The mechanism of proliferation is thought to result from photo-stimulation of the mitochondria leading to activation of signaling pathways and up regulation of transcription factors eventually giving rise to increases in growth factors . LLLT (low level laser therapie) can enhance neovascularization, promote angiogenesis and increase collagen synthesis to aid in the healing of acute and chronic wounds . It has been observed in many studies, that LLLT (low level laser therapie) exhibits a biphasic dose response curve, where by lower doses of light are more effective than much higher doses. These low doses of light have demonstrated the ability to heal skin, nerves, tendons, cartilage and bones.

mitochondriaLow Level Laser Therapy (LLLT (low level laser therapie)) has a photochemical effect (like photosynthesis in plants). One of the main mechanisms of action occurs in the mitochondria (the cellular power plant inside every cell). The effect depend on the application of the correct wavelength and density of light, delivered to the target tissues for an appropriate period of time (typically between 30 – 60 seconds). Pulses can improve tissue repair and anti-inflammatory effect, analgesia is best achieved with a continuous beam.


The primary effect occurs when light is absorbed in cytochrome c oxidase a protein within the mitochondria.

When cells get stressed (perhaps due to disease, injury or ageing) the mitochondria produces nitric oxide (NO). This competitively displaces oxygen from cytochrome c oxidase consequently reducing ATP (an essential intracellular cellular energy and extracellular signalling molecule) and causing an over production reactive oxygen species (ROS) and leading to oxidative stress. Oxidative stress is well known to lead to inflammation an cell death via the gene transcription factor NF-Kb.

Low Level Laser Therapy (LLLT (low level laser therapie)) of the correct wavelength and density, dissociates NO allowing oxygen back in, so ATP is restored and oxidative stress reduced. Once normal mitochondrial function is restored by LLLT (low level laser therapie) then cell metabolism is improves, and the patient gets better more quickly.

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How to Find Low-Level Laser Therapy

Many massage therapists, acupuncturists, chiropractors, physical therapists, and other health care professionals use LLLT in their healing practices, and it may be easiest to find them in your area by asking your physician for a referral or searching online. The World Association for Laser Therapy sponsors Find a Laser Therapist to help you find a laser therapist in your area; however, know that the current therapist list is short.

Many companies now manufacture and sell low-level lasers to the general public; however, quality lasers can be quite pricey, ranging up to $25,000 or more, and there are many complex options to choose from. To provide an alternative to purchasing a laser for home use, some therapists rent their lasers to clients.


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